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The intravenous drug has been injected into over 600,000 patients across the nation to treat heart failure. Nesiritide is sold as Natrecor and is made by Scios Inc., a subsidiary of Johnson & Johnson. The medication was approved in 2001, but researchers recently discovered patients were more likely to die in the first month after treatment than if they were to have taken a placebo.

What is Natrecor?
Natrecor causes the relaxation and enlargement of blood vessels, which lowers blood pressure, especially in the blood vessels in the lungs and heart. Natrecor is used to improve shortness of breath due to congestive heart failure (CHF).

  • Natrecor is a prescription drug approved by the FDA as a therapy for hospitalized patients or those rushed to emergency rooms in acute heart failure.
  • Natrecor, a drug used to treat heart failure, can worsen kidney function and make patients more likely to die, U.S. researchers reported.
  • Nesiritide, marketed as Natrecor, won FDA approval in 2001. Scios Inc. is a subsidiary of Johnson & Johnson.
  • Nesiritide was associated with a 40 to 50 percent higher risk of worsening kidney function when used for the treatment of acutely decompensated heart failure. And, whether using low or high doses, nesiritide was associated with significant risk of kidney dysfunction.

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